The winning numbers for Friday night's drawing were 3, 21, 29, 46, 63, and the Mega Ball was 9. The Megaplier was 3X. Hoosier Lotto Overall Odds 1 in 6 The next Powerball drawing is Saturday, Nov. 5. Drawings are held at 10:59 p.m. every Monday, Wednesday and Saturday. The content and operations of this website have not been approved or endorsed by